Chef Secrets for Spicy Catfish. Cajun Fried Catfish is a wonderful way to enjoy Southern cuisine. This dish is seasoned and deep-fried until golden, showcasing the rich flavors of Louisiana. You’ll find helpful tips for making the fish crispy and ideas for tasty side dishes to go along with it. Whether you’re having friends over or just a family meal, this catfish recipe is sure to be a hit. It’s a classic comfort food that you’ll want to try.